MolNFT v1 · #93303 · protein

Crystal structure of the RIO2 kinase from chaetomium thermophilum

4GYG: “Crystal structure of the RIO2 kinase from chaetomium thermophilum”. X-ray diffraction, 5 pockets (best druggability 0.67). MolNFT v1 #93303 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4GYG
Type: protein
Length: 331 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RIO2 kinase
UniProt: G0S5R3
Pockets: 5 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RIO2 kinase	protein	331	42% helix, 20% strand	G0S5R3

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	392	0.67	0.80	45	empty
2	155	0.49	0.77	20	empty
3	128	0.45	0.77	20	empty
4	59	0.28	0.74	13	empty
5	51	0.26	0.74	15	empty

Compared structures

4GYG · Crystal structure of the Rio2 kinase from Chaetomium thermophilum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S5R3
Elsewhere: RCSB PDB 4GYG · PDBe 4GYG · UniProt G0S5R3

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