MolNFT v1 · #93279 · protein
Chimeric family 1 beta-glucosidase made with non-contiguous schema
4GXP · Beta-glucosidase chimeric protein: “Chimeric family 1 beta-glucosidase made with non-contiguous schema”. X-ray diffraction, 18 pockets (best druggability 0.88). MolNFT v1 #93279 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4GXP
- Type
- protein
- Length
- 1,366 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-glucosidase chimeric protein
- EC
- 3.2.1.21
- UniProt
- Q08638, O93785
- Pockets
- 18 · best druggability 0.88
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Beta-glucosidase chimeric protein (EC 3.2.1.21) | protein | 456 | 43% helix, 16% strand | Q08638, O93785 |
| C | Beta-glucosidase chimeric protein (EC 3.2.1.21) | protein | 454 | 39% helix, 13% strand | Q08638, O93785 |
Pockets
18 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1182 | 0.88 | 0.89 | 144 | empty |
| 2 | 90 | 0.78 | 0.98 | 27 | empty |
| 3 | 180 | 0.75 | 0.91 | 42 | empty |
| 4 | 368 | 0.73 | 0.84 | 54 | empty |
| 5 | 485 | 0.72 | 0.81 | 50 | empty |
Interfaces
2 interfaces between chains.
- A–B · 822 Ų buried · 11 hydrogen bonds · protein-protein
- B–C · 693 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08638
- Every structure of UniProt O93785
- Elsewhere: RCSB PDB 4GXP · PDBe 4GXP · UniProt Q08638 · UniProt O93785
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.