MolNFT v1 · #92043 · protein

Crystal structure of EV71 2A proteinase C110A mutant

4FVB: “Crystal structure of EV71 2A proteinase C110A mutant”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.49). MolNFT v1 #92043 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4FVB
Type: protein
Length: 138 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 2A proteinase
EC: 3.4.22.29
UniProt: A9XG43
Ligands: ZN
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	2A proteinase (EC 3.4.22.29)	protein	138	10% helix, 48% strand	A9XG43

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	161	0.49	0.78	30	empty

Compared structures

4FVB · Crystal structure of EV71 2A proteinase C110A mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A9XG43
Elsewhere: RCSB PDB 4FVB · PDBe 4FVB · UniProt A9XG43

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