UniProt A9XG43
3C proteinase (A9XG43)
3C proteinase (UniProt A9XG43), EC 3.4.22.28: 29 experimental structures on GenesisL1, 7 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A9XG43
- Protein
- 3C proteinase
- EC
- 3.4.22.28
- Experimental structures
- 29
- Predicted models
- 0
- Ligands
- 7
Structures
29 records of A9XG43 in the MolNFT archive: 29 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4FVB | Crystal structure of EV71 2A proteinase C110A mutant | x-ray diffraction | A | — | — |
| 4FVB | Crystal structure of EV71 2A proteinase C110A mutant | x-ray diffraction | A | — | — |
| 4FVD | Crystal structure of EV71 2A proteinase C110A mutant in complex with substrate | x-ray diffraction | A, C | — | — |
| 4FVD | Crystal structure of EV71 2A proteinase C110A mutant in complex with substrate | x-ray diffraction | A, C | — | — |
| 4GHQ | Crystal structure of EV71 3C proteinase | x-ray diffraction | A | — | — |
| 4GHQ | Crystal structure of EV71 3C proteinase | x-ray diffraction | A | — | — |
| 4GHT | Crystal structure of EV71 3C proteinase in complex with AG7088 | x-ray diffraction | A, B | — | — |
| 4GHT | Crystal structure of EV71 3C proteinase in complex with AG7088 | x-ray diffraction | A, B | — | — |
| 5C1U | Crystal structure of EV71 3C Proteinase in complex with Compound Xb | x-ray diffraction | A, B | — | — |
| 5C1U | Crystal structure of EV71 3C proteinase in complex with compound xb | x-ray diffraction | A, B | — | — |
| 5C1X | Crystal structure of EV71 3C proteinase in complex with compound VIII | x-ray diffraction | A, B | — | — |
| 5C1Y | Crystal structure of EV71 3C Proteinase in complex with Compound 1 | x-ray diffraction | A | GHY | — |
| 5C1Y | Crystal structure of EV71 3C proteinase in complex with compound 1 | x-ray diffraction | A | — | — |
| 5C20 | Crystal structure of EV71 3C proteinase in complex with compound 2 | x-ray diffraction | A | — | — |
| 5DP3 | Crystal structure of EV71 3C proteinase in complex with compound 2 | x-ray diffraction | A | — | — |
| 5DP4 | Crystal Structure of EV71 3C Proteinase in complex with compound 3 | x-ray diffraction | A, B, C, D | 5E8 | — |
| 5DP4 | Crystal structure of EV71 3C proteinase in complex with compound 3 | x-ray diffraction | A, B, C, D | — | — |
| 5DP5 | Crystal Structure of EV71 3C Proteinase in complex with compound 4 | x-ray diffraction | A | 5E9 | — |
| 5DP5 | Crystal structure of EV71 3C proteinase in complex with compound 4 | x-ray diffraction | A | — | — |
| 5DP6 | Crystal Structure of EV71 3C Proteinase in complex with compound 7 | x-ray diffraction | A, B, C, D | 5EB | — |
| 5DP6 | Crystal structure of EV71 3C proteinase in complex with compound 7 | x-ray diffraction | A, B, C, D | — | — |
| 5DP7 | Crystal structure of EV71 3C proteinase in complex with compound 5 | x-ray diffraction | A | — | — |
| 5DP8 | Crystal Structure of EV71 3C Proteinase in complex with compound 8 | x-ray diffraction | A | 5ED | — |
| 5DP8 | Crystal structure of EV71 3C proteinase in complex with compound 8 | x-ray diffraction | A | — | — |
| 5DP9 | Crystal Structure of EV71 3C Proteinase in complex with compound 9 | x-ray diffraction | A | 5EX | — |
| 5DP9 | Crystal structure of EV71 3C proteinase in complex with compound 9 | x-ray diffraction | A | — | — |
| 5DPA | Crystal structure of EV71 3C proteinase in complex with compound 6 | x-ray diffraction | A | — | — |
| 6LKA | Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds | x-ray diffraction | A | EGF | — |
| 6LKA | Crystal structure of EV71-3C protease with a novel macrocyclic compounds | x-ray diffraction | A | EGF | — |
Ligands
- EGF · ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide · in 2 records
- 5E8 · ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate · in 1 record
- 5E9 · ethyl (2Z,4S)-4-{[(2R,5S)-5-amino-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate · in 1 record
- 5EB · ethyl (2Z,4S)-4-{[N-(3-cyclopropylpropanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate · in 1 record
- 5ED · ethyl (2Z,4S)-4-[(N-{[(2-cyclopropylethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate · in 1 record
- 5EX · ethyl (2Z,4S)-4-[(N-{[(cyclobutylmethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate · in 1 record
- GHY · propan-2-yl N-[(2S)-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-3-phenyl-propan-2-yl]carbamate · in 1 record
Elsewhere
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