MolNFT v1 · #91946 · protein
Arsm ARSENIC(III) S-adenosylmethionine methyltransferase with AS(III)
4FSD · Arsenic methyltransferase: “Arsm ARSENIC(III) S-adenosylmethionine methyltransferase with AS(III)”. X-ray diffraction, 3 ligands (CA, ARS, CL), 2 pockets (best druggability 0.55). MolNFT v1 #91946 on GenesisL1: 3D structure, binding…
- PDB
- 4FSD
- Type
- protein
- Length
- 322 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Arsenic methyltransferase
- UniProt
- C0JV69
- Ligands
- CA, ARS, CL
- Pockets
- 2 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Arsenic methyltransferase | protein | 322 | 35% helix, 24% strand | C0JV69 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
- ARS · Arsenic · metal · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 158 | 0.55 | 0.80 | 23 | CA |
| 2 | 85 | 0.35 | 0.75 | 26 | empty |
Compared structures
- 4FSD · ArsM arsenic(III) S-adenosylmethionine methyltransferase with As(III) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C0JV69
- Elsewhere: RCSB PDB 4FSD · PDBe 4FSD · UniProt C0JV69
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