MolNFT v1 · #91359 · RNA

Structure of oceanobacillus iheyensis group II intron C377G mutant in a ligand-free state in the presence of K+ and MG2+

4FB0 · Group iic intron: “Structure of oceanobacillus iheyensis group II intron C377G mutant in a ligand-free state in the presence of…”. X-ray diffraction, 3 ligands (SPM, MG, K), 15 pockets (best druggability 0.76). MolNFT v1 #91359 on…

PDB: 4FB0
Type: RNA
Length: 392 nucleotides
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Group iic intron
Ligands: SPM, MG, K
Pockets: 15 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Group iic intron	rna	392	—	—

Ligands and binding sites

SPM · Spermine · ligand · chains A
MG · Magnesium ion · metal · 25 copies · chains A
K · Potassium ion · metal · 18 copies · chains A
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	892	0.76	0.80	65	MG
2	712	0.66	0.76	57	MG, K
3	727	0.66	0.75	50	MG, K
4	235	0.63	0.83	21	MG
5	618	0.61	0.74	35	MG, K, SPM

Compared structures

4FB0 · Structure of Oceanobacillus iheyensis group II intron C377G mutant in a ligand-free state… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4FB0 · PDBe 4FB0

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