MolNFT v1 · #91355 · RNA
Structure of oceanobacillus iheyensis group II intron in the presence of K+, MG2+ and a hydrolyzed oligonucleotide fragment
4FAW · Group iic intron: “Structure of oceanobacillus iheyensis group II intron in the presence of K+, MG2+ and a hydrolyzed…”. X-ray diffraction, 3 ligands (SPM, MG, K), 17 pockets (best druggability 0.69). MolNFT v1 #91355 on GenesisL1…
- PDB
- 4FAW
- Type
- RNA
- Length
- 395 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Group iic intron; 5'-R(*A*UP*UP*UP*AP*UP*UP*A)-3'
- Ligands
- SPM, MG, K
- Pockets
- 17 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Group iic intron | rna | 390 | — | — |
| B | 5'-R(*A*UP*UP*UP*AP*UP*UP*A)-3' | rna | 5 | — | — |
Ligands and binding sites
- SPM · Spermine · ligand · chains A
- MG · Magnesium ion · metal · 32 copies · chains A, B
- K · Potassium ion · metal · 19 copies · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 453 | 0.69 | 0.81 | 42 | MG |
| 2 | 450 | 0.66 | 0.80 | 33 | MG |
| 3 | 696 | 0.66 | 0.76 | 46 | MG, K |
| 4 | 401 | 0.66 | 0.80 | 29 | MG |
| 5 | 675 | 0.65 | 0.76 | 53 | MG, K |
Interfaces
1 interface between chains.
- A–B · 387 Ų buried · 24 hydrogen bonds · nucleic-nucleic
Compared structures
- 4FAW · Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+ and a… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4FAW · PDBe 4FAW
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