MolNFT v1 · #91295 · protein
BRR2 helicase region
4F91 · U5 small nuclear ribonucleoprotein 200 kda helicase: “BRR2 helicase region”. X-ray diffraction, 20 pockets (best druggability 0.84). MolNFT v1 #91295 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4F91
- Type
- protein
- Length
- 1,724 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- U5 small nuclear ribonucleoprotein 200 kda helicase
- EC
- 3.6.4.13
- UniProt
- O75643
- Pockets
- 20 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | U5 small nuclear ribonucleoprotein 200 kda helicase (EC 3.6.4.13) | protein | 1724 | 42% helix, 17% strand | O75643 |
Pockets
20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 838 | 0.84 | 0.86 | 102 | empty |
| 2 | 467 | 0.80 | 0.88 | 71 | empty |
| 3 | 169 | 0.77 | 0.93 | 23 | empty |
| 4 | 437 | 0.75 | 0.84 | 51 | empty |
| 5 | 661 | 0.74 | 0.80 | 45 | empty |
Compared structures
- 4F91 · Brr2 Helicase Region · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75643
- Elsewhere: RCSB PDB 4F91 · PDBe 4F91 · UniProt O75643
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