MolNFT v1 · #9125 · protein
Crystal structure of S.PNEUMONIAE N-acetylglucosamine 1-phosphate uridyltransferase, glmu
1HM0: “Crystal structure of S.PNEUMONIAE N-acetylglucosamine 1-phosphate uridyltransferase, glmu”. X-ray diffraction, 1 ligand (CA), 4 pockets (best druggability 0.65). MolNFT v1 #9125 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1HM0
- Type
- protein
- Length
- 880 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- N-acetylglucosamine 1-phosphate uridyltransferase
- EC
- 2.7.7.23
- UniProt
- Q97R46
- Ligands
- CA
- Pockets
- 4 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | N-acetylglucosamine 1-phosphate uridyltransferase (EC 2.7.7.23) | protein | 440 | 22% helix, 29% strand | Q97R46 |
Ligands and binding sites
- CA · Calcium ion · metal · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 464 | 0.65 | 0.77 | 47 | empty |
| 2 | 483 | 0.62 | 0.75 | 45 | empty |
| 3 | 74 | 0.34 | 0.76 | 15 | empty |
| 4 | 66 | 0.32 | 0.75 | 14 | empty |
Compared structures
- 1HM0 · Crystal structure of S.PNEUMONIAE N-acetylglucosamine 1-phosphate uridyltransferase, glmu · the same entry in another collection · chain A against A, TM-score 1.00
- Q97R46 · AlphaFold monomer V2.0 prediction for bifunctional protein glmu (Q97R46) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97R46
- Elsewhere: RCSB PDB 1HM0 · PDBe 1HM0 · UniProt Q97R46
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