GL1X · GenesisL1 explorer

MolNFT v1 · #91230 · protein

Crystal structure of human CDK8/CYCC in complex with compound 4 (1-[3- tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[2-(morpholin-4-yl) ETHYL]UREA)

4F70: “Crystal structure of human CDK8/CYCC in complex with compound 4 (1-[3…”. X-ray diffraction. MolNFT v1 #91230 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
4F70
Type
protein
Length
593 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P49336, P24863

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein327—P49336
B—protein266—P24863

Compared structures

  • 4F70 · Crystal structure of human CDK8/CYCC in complex with compound 4… · the same entry in another collection · chain B against B, TM-score 1.00
  • P49336 · AlphaFold monomer V2.0 prediction for cyclin-dependent kinase 8 (P49336) · a predicted model of the same protein · chain A against A, TM-score 0.99
  • P24863 · AlphaFold monomer V2.0 prediction for cyclin-C (P24863) · a predicted model of the same protein · chain B against A, TM-score 0.99

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