MolNFT v1 · #89210 · protein
Crystal structure of phosphoribosylglycinamide synthetase from anaerococcus prevotii
4DIM: “Crystal structure of phosphoribosylglycinamide synthetase from anaerococcus prevotii”. X-ray diffraction, 7 pockets (best druggability 0.72). MolNFT v1 #89210 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4DIM
- Type
- protein
- Length
- 393 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosylglycinamide synthetase
- UniProt
- C7RDM8
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoribosylglycinamide synthetase | protein | 393 | 34% helix, 30% strand | C7RDM8 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.72 | 0.99 | 20 | empty |
| 2 | 451 | 0.63 | 0.77 | 61 | empty |
| 3 | 118 | 0.42 | 0.75 | 18 | empty |
| 4 | 69 | 0.31 | 0.74 | 17 | empty |
| 5 | 53 | 0.31 | 0.76 | 13 | empty |
Modifications
Observed in the structure: 11 modified (engineered).
Compared structures
- 4DIM · Crystal structure of phosphoribosylglycinamide synthetase from Anaerococcus prevotii · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C7RDM8
- Elsewhere: RCSB PDB 4DIM · PDBe 4DIM · UniProt C7RDM8
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