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Crystal structure of phosphoribosylglycinamide synthetase from anaerococcus prevotii

Analyse Crystal structure of phosphoribosylglycinamide synthetase from anaerococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4DIM
Type
protein
Length
393 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Phosphoribosylglycinamide synthetase
UniProt
C7RDM8
Pockets
7 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APhosphoribosylglycinamide synthetaseprotein39334% helix, 30% strandC7RDM8

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1500.720.9920empty
24510.630.7761empty
31180.420.7518empty
4690.310.7417empty
5530.310.7613empty

Modifications

Observed in the structure: 11 modified (engineered).

Compared structures

  • 4DIM · Crystal structure of phosphoribosylglycinamide synthetase from Anaerococcus prevotii · the same entry in another collection · chain A against A, TM-score 1.00

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