DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5A tail

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 37% strand (DSSP).

Ligands and binding sites

• CO · Cobalt (II) ion · metal · chains A
• SO4 · Sulfate ion · ion · chains A
• TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 655 Ų buried · 19 hydrogen bonds · protein-protein

Compared structures

• 4D07 · DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5a… · the same entry in another collection · chain A against A, TM-score 1.00
• Q96FJ2 · AlphaFold monomer V2.0 prediction for dynein light chain 2, cytoplasmic (Q96FJ2) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q96FJ2
• Every structure of UniProt Q59FF5
• Elsewhere: RCSB PDB 4D07 · PDBe 4D07 · UniProt Q96FJ2 · UniProt Q59FF5