MolNFT v1 · #8831 · protein
Human cyclin-dependent kinase 2
1HCL: “Human cyclin-dependent kinase 2”. X-ray diffraction, 2 pockets (best druggability 0.68). MolNFT v1 #8831 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1HCL
- Type
- protein
- Length
- 294 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Human cyclin-dependent kinase 2
- EC
- 2.7.1.37
- UniProt
- P24941
- Pockets
- 2 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Human cyclin-dependent kinase 2 (EC 2.7.1.37) | protein | 294 | 34% helix, 16% strand | P24941 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 310 | 0.68 | 0.83 | 40 | empty |
| 2 | 66 | 0.30 | 0.74 | 15 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24941
- Elsewhere: RCSB PDB 1HCL · PDBe 1HCL · UniProt P24941
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