MolNFT v1 · #88241 · protein

The importance of the ABN2 calcium cluster in the endo-1,5- arabinanase activity from bacillus subtilis

4COT · Extracellular endo-alpha-(1->5)-L-arabinanase 2: “The importance of the ABN2 calcium cluster in the endo-1,5- arabinanase activity from bacillus subtilis”. X-ray diffraction, 1 ligand (NI), 4 pockets (best druggability 0.62). MolNFT…

PDB: 4COT
Type: protein
Length: 443 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Extracellular endo-alpha-(1->5)-L-arabinanase 2
EC: 3.2.1.99
UniProt: B3FRL6
Ligands: NI
Pockets: 4 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Extracellular endo-alpha-(1->5)-L-arabinanase 2 (EC 3.2.1.99)	protein	443	6% helix, 44% strand	B3FRL6

Ligands and binding sites

NI · Nickel (II) ion · metal · chains A
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	340	0.62	0.78	22	empty
2	172	0.47	0.76	26	TRS
3	105	0.46	0.79	24	empty
4	62	0.37	0.78	19	empty

Compared structures

4COT · The importance of the Abn2 calcium cluster in the endo-1,5- arabinanase activity from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B3FRL6
Elsewhere: RCSB PDB 4COT · PDBe 4COT · UniProt B3FRL6

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