MolNFT v1 · #88238 · protein
HIV-1 capsid C-terminal domain mutant (Y169S)
4COP · Capsid protein P24: “HIV-1 capsid C-terminal domain mutant (Y169S)”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #88238 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4COP
- Type
- protein
- Length
- 152 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein P24
- UniProt
- P12497
- Pockets
- 1 · best druggability 0.34
Structure
x-ray diffraction · 2 distinct chains · 64% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Capsid protein P24 | protein | 84 | 58% helix, 0% strand | P12497 |
| B | Capsid protein P24 | protein | 68 | 71% helix, 0% strand | P12497 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 74 | 0.34 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 515 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 4COP · HIV-1 capsid C-terminal domain mutant (Y169S) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12497
- Elsewhere: RCSB PDB 4COP · PDBe 4COP · UniProt P12497
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