MolNFT v1 · #88197 · protein
L-aminoacetone oxidase from streptococcus oligofermentans belongs to a new 3-domain family of bacterial flavoproteins
4CNJ · L-amino acid oxidase: “L-aminoacetone oxidase from streptococcus oligofermentans belongs to a new 3-domain family of bacterial…”. X-ray diffraction, 1 ligand (FAD), 13 pockets (best druggability 0.79). MolNFT v1 #88197 on GenesisL1…
- PDB
- 4CNJ
- Type
- protein
- Length
- 1,564 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-amino acid oxidase
- EC
- 1.1.3.2
- UniProt
- B1PUC6
- Ligands
- FAD
- Pockets
- 13 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | L-amino acid oxidase (EC 1.1.3.2) | protein | 391 | 36% helix, 25% strand | B1PUC6 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
13 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 545 | 0.79 | 0.85 | 72 | FAD |
| 2 | 539 | 0.79 | 0.85 | 76 | FAD |
| 3 | 550 | 0.78 | 0.85 | 80 | FAD |
| 4 | 540 | 0.77 | 0.84 | 75 | FAD |
| 5 | 637 | 0.77 | 0.83 | 107 | empty |
Interfaces
5 interfaces between chains.
- C–D · 533 Ų buried · 2 hydrogen bonds · protein-protein
- A–D · 450 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 443 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 435 Ų buried · 5 hydrogen bonds · protein-protein
- A–B · 181 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4CNJ · L-Aminoacetone oxidase from Streptococcus oligofermentans belongs to a new 3-domain… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B1PUC6
- Elsewhere: RCSB PDB 4CNJ · PDBe 4CNJ · UniProt B1PUC6
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