MolNFT v1 · #88051 · protein
Crystal structure of the complex of the cellular retinal binding protein mutant R234W with 9-cis-retinal
4CJ6 · Retinaldehyde-binding protein 1: “Crystal structure of the complex of the cellular retinal binding protein mutant R234W with 9-cis-retinal”. X-ray diffraction, 1 ligand (RET), 5 pockets (best druggability 0.83). MolNFT v1 #88051 on…
- PDB
- 4CJ6
- Type
- protein
- Length
- 250 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Retinaldehyde-binding protein 1
- UniProt
- P12271
- Ligands
- RET
- Pockets
- 5 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Retinaldehyde-binding protein 1 | protein | 250 | 56% helix, 10% strand | P12271 |
Ligands and binding sites
- RET · Retinal · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 212 | 0.83 | 0.95 | 26 | RET |
| 2 | 161 | 0.45 | 0.75 | 22 | empty |
| 3 | 72 | 0.40 | 0.79 | 15 | empty |
| 4 | 62 | 0.30 | 0.74 | 15 | empty |
| 5 | 54 | 0.30 | 0.76 | 15 | empty |
Compared structures
- 4CJ6 · Crystal structure of the complex of the Cellular Retinal Binding Protein Mutant R234W… · the same entry in another collection · chain A against A, TM-score 1.00
- P12271 · AlphaFold monomer V2.0 prediction for retinaldehyde-binding protein 1 (P12271) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12271
- Elsewhere: RCSB PDB 4CJ6 · PDBe 4CJ6 · UniProt P12271
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