MolNFT v1 · #87653 · protein

Crystal structure of the synthetic peptide IM10 in complex with the coiled-coil region of mitf

4C7N · Microphthalmia associated transcription factor: “Crystal structure of the synthetic peptide IM10 in complex with the coiled-coil region of mitf”. X-ray diffraction, 1 ligand (HG). MolNFT v1 #87653 on GenesisL1: 3D structure, binding…

PDB: 4C7N
Type: protein
Length: 98 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Microphthalmia associated transcription factor; Synthetic alpha-helix, IM10
UniProt: O75030
Ligands: HG

Structure

x-ray diffraction · 2 distinct chains · 91% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Microphthalmia associated transcription factor	protein	47	96% helix, 0% strand	O75030
B	Synthetic alpha-helix, IM10	protein	51	86% helix, 0% strand	—

Ligands and binding sites

HG · Mercury (II) ion · metal · 6 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 1336 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

4C7N · Crystal Structure of the synthetic peptide iM10 in complex with the coiled-coil region of… · the same entry in another collection · chain A against A, TM-score 1.00
O75030 · AlphaFold monomer V2.0 prediction for microphthalmia-associated transcription factor… · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O75030
Elsewhere: RCSB PDB 4C7N · PDBe 4C7N · UniProt O75030

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.