UniProt O75030
Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit (O75030)
Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit (UniProt O75030): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and…
- UniProt
- O75030
- Protein
- Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta…
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 3 records with a druggable one
Structures
11 records of O75030 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C7N | Crystal Structure of the synthetic peptide iM10 in complex with the coiled-coil region of MITF | x-ray diffraction | A | — | — |
| 4C7N | Crystal structure of the synthetic peptide IM10 in complex with the coiled-coil region of mitf | x-ray diffraction | A | — | — |
| 7D8R | MITF HLHLZ structure | x-ray diffraction | A, B, C, D | — | 4 (best 0.56) |
| 7D8R | Mitf hlhlz structure | x-ray diffraction | A, B, C, D | — | — |
| 7D8S | MITF bHLHLZ apo structure | x-ray diffraction | A, B, C, D | SO4 | 10 (best 0.65) |
| 7D8S | Mitf bhlhlz apo structure | x-ray diffraction | A, B, C, D | SO4 | — |
| 7D8T | MITF bHLHLZ complex with M-box DNA | x-ray diffraction | A, B | — | 6 (best 0.83) |
| 7D8T | Mitf bhlhlz complex with M-box DNA | x-ray diffraction | A, B | — | — |
| 7EOD | Mitf hlhlz delta ake | x-ray diffraction | — | — | |
| 8E1D | NMR-derived ensemble of the TAZ2 domain of p300 bound to the microphthalmia-associated… | solution nmr | B | — | — |
| O75030 | AlphaFold monomer V2.0 prediction for microphthalmia-associated transcription factor (O75030) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 4C7N chain A against the predicted model O75030: TM-score 0.81, RMSD 1.40 Å
- 4C7N chain A against the predicted model O75030: TM-score 0.81, RMSD 1.40 Å
- 8E1D chain B against the predicted model O75030: TM-score 0.46, RMSD 2.30 Å
- 7D8T chain A against the predicted model O75030: TM-score 0.45, RMSD 3.35 Å
- 7D8T chain A against the predicted model O75030: TM-score 0.45, RMSD 3.35 Å
- 7D8S chain C against the predicted model O75030: TM-score 0.39, RMSD 4.22 Å
- 7D8S chain C against the predicted model O75030: TM-score 0.39, RMSD 4.22 Å
- 7D8T chain B against the predicted model O75030: TM-score 0.39, RMSD 3.26 Å
- 7D8S chain A against the predicted model O75030: TM-score 0.39, RMSD 3.84 Å
- 7D8S chain A against the predicted model O75030: TM-score 0.39, RMSD 3.84 Å
Elsewhere
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