MolNFT v1 · #85921 · protein
Crystal structure of the peptidase domain of collagenase H from clostridium histolyticum at 2.01 ångström resolution.
4AR1 · Colh protein: “Crystal structure of the peptidase domain of collagenase H from clostridium histolyticum at 2.01 ångström…”. X-ray diffraction, 2 ligands (ZN, CA), 5 pockets (best druggability 0.67). MolNFT v1 #85921 on GenesisL1: 3D…
- PDB
- 4AR1
- Type
- protein
- Length
- 381 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Colh protein
- UniProt
- Q46085
- Ligands
- ZN, CA
- Pockets
- 5 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Colh protein | protein | 381 | 50% helix, 19% strand | Q46085 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 219 | 0.67 | 0.85 | 29 | empty |
| 2 | 117 | 0.60 | 0.86 | 21 | empty |
| 3 | 79 | 0.46 | 0.81 | 21 | empty |
| 4 | 53 | 0.38 | 0.80 | 11 | empty |
| 5 | 78 | 0.38 | 0.77 | 18 | empty |
Compared structures
- 4AR1 · Crystal Structure of the Peptidase Domain of Collagenase H from Clostridium histolyticum… · the same entry in another collection · chain A against A, TM-score 1.00
- Q46085 · AlphaFold monomer V2.0 prediction for collagenase colh (Q46085) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q46085
- Elsewhere: RCSB PDB 4AR1 · PDBe 4AR1 · UniProt Q46085
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.