MolNFT v1 · #85801 · protein
Crystal form II of the D93N mutant of nucleoside diphosphate kinase from mycobacterium tuberculosis
4AND: “Crystal form II of the D93N mutant of nucleoside diphosphate kinase from mycobacterium tuberculosis”. X-ray diffraction, 2 pockets (best druggability 0.47). MolNFT v1 #85801 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4AND
- Type
- protein
- Length
- 265 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoside diphosphate kinase
- EC
- 2.7.4.6
- UniProt
- P84284
- Pockets
- 2 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoside diphosphate kinase (EC 2.7.4.6) | protein | 135 | 44% helix, 19% strand | P84284 |
| B | Nucleoside diphosphate kinase (EC 2.7.4.6) | protein | 130 | 43% helix, 20% strand | P84284 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 183 | 0.47 | 0.76 | 32 | empty |
| 2 | 152 | 0.42 | 0.74 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 694 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 4AND · Crystal form II of the D93N mutant of nucleoside diphosphate kinase from mycobacterium… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P84284
- Elsewhere: RCSB PDB 4AND · PDBe 4AND · UniProt P84284
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.