Research workbench
Crystal form II of the D93N mutant of nucleoside diphosphate kinase from mycobacterium tuberculosis
Analyse Crystal form II of the D93N mutant of nucleoside diphosphate kinase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4AND
- Type
- protein
- Length
- 265 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoside diphosphate kinase
- EC
- 2.7.4.6
- UniProt
- P84284
- Pockets
- 2 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoside diphosphate kinase (EC 2.7.4.6) | protein | 135 | 44% helix, 19% strand | P84284 |
| B | Nucleoside diphosphate kinase (EC 2.7.4.6) | protein | 130 | 43% helix, 20% strand | P84284 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 183 | 0.47 | 0.76 | 32 | empty |
| 2 | 152 | 0.42 | 0.74 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 694 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 4AND · Crystal form II of the D93N mutant of nucleoside diphosphate kinase from mycobacterium… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P84284
- Elsewhere: RCSB PDB 4AND · PDBe 4AND · UniProt P84284
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