MolNFT v1 · #84365 · protein

Structure of the WPL1 protein

3ZIK: “Structure of the WPL1 protein”. X-ray diffraction, 6 pockets (best druggability 0.66). MolNFT v1 #84365 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3ZIK
Type: protein
Length: 725 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: WPL1
UniProt: Q75E93
Pockets: 6 · best druggability 0.66

Structure

x-ray diffraction · 2 distinct chains · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	WPL1	protein	368	67% helix, 0% strand	Q75E93
B	WPL1	protein	357	71% helix, 0% strand	Q75E93

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	588	0.66	0.76	58	empty
2	335	0.60	0.77	34	empty
3	131	0.48	0.79	18	empty
4	73	0.37	0.77	15	empty
5	54	0.35	0.78	11	empty

Interfaces

1 interface between chains.

A–B · 630 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

3ZIK · Structure of the Wpl1 protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q75E93
Elsewhere: RCSB PDB 3ZIK · PDBe 3ZIK · UniProt Q75E93

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