Research workbench
Structure of the WPL1 protein
Analyse Structure of the WPL1 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ZIK
- Type
- protein
- Length
- 725 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- WPL1
- UniProt
- Q75E93
- Pockets
- 6 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | WPL1 | protein | 368 | 67% helix, 0% strand | Q75E93 |
| B | WPL1 | protein | 357 | 71% helix, 0% strand | Q75E93 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 588 | 0.66 | 0.76 | 58 | empty |
| 2 | 335 | 0.60 | 0.77 | 34 | empty |
| 3 | 131 | 0.48 | 0.79 | 18 | empty |
| 4 | 73 | 0.37 | 0.77 | 15 | empty |
| 5 | 54 | 0.35 | 0.78 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 630 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 3ZIK · Structure of the Wpl1 protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q75E93
- Elsewhere: RCSB PDB 3ZIK · PDBe 3ZIK · UniProt Q75E93
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