MolNFT v1 · #84265 · protein
Crystal structure of pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase
3ZFH: “Crystal structure of pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.46). MolNFT v1 #84265 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 3ZFH
- Type
- protein
- Length
- 299 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inosine 5'-monophosphate dehydrogenase
- EC
- 1.1.1.205
- UniProt
- Q9HXM5
- Ligands
- CL
- Pockets
- 2 · best druggability 0.46
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inosine 5'-monophosphate dehydrogenase (EC 1.1.1.205) | protein | 299 | 38% helix, 16% strand | Q9HXM5 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 207 | 0.46 | 0.74 | 25 | empty |
| 2 | 50 | 0.25 | 0.73 | 13 | empty |
Compared structures
- 3ZFH · Crystal structure of Pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HXM5
- Elsewhere: RCSB PDB 3ZFH · PDBe 3ZFH · UniProt Q9HXM5
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