MolNFT v1 · #83727 · protein

The crystal structure of native HYPBA1 from bifidobacterium longum jcm 1217

3WRF · Non-reducing end beta-L-arabinofuranosidase: “The crystal structure of native HYPBA1 from bifidobacterium longum jcm 1217”. X-ray diffraction, 5 pockets (best druggability 0.69). MolNFT v1 #83727 on GenesisL1: 3D structure, binding…

PDB: 3WRF
Type: protein
Length: 639 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Non-reducing end beta-L-arabinofuranosidase
EC: 3.2.1.185
UniProt: E8MGH8
Pockets: 5 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Non-reducing end beta-L-arabinofuranosidase (EC 3.2.1.185)	protein	639	38% helix, 18% strand	E8MGH8

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	442	0.69	0.80	41	empty
2	412	0.68	0.80	41	empty
3	327	0.60	0.77	38	empty
4	147	0.54	0.81	24	empty
5	57	0.34	0.78	15	empty

Modifications

Observed in the structure: 15 modified (engineered).

Compared structures

3WRF · The crystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 · the same entry in another collection · chain A against A, TM-score 1.00
E8MGH8 · AlphaFold monomer V2.0 prediction for non-reducing end beta-L- arabinofuranosidase… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E8MGH8
Elsewhere: RCSB PDB 3WRF · PDBe 3WRF · UniProt E8MGH8

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