UniProt E8MGH8
Non-reducing end beta-L-arabinofuranosidase (E8MGH8)
Non-reducing end beta-L-arabinofuranosidase (UniProt E8MGH8), EC 3.2.1.185: 21 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- E8MGH8
- Protein
- Non-reducing end beta-L-arabinofuranosidase
- EC
- 3.2.1.185
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 19 · 6 records with a druggable one
Structures
22 records of E8MGH8 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WKW | Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand… | x-ray diffraction | A | — | — |
| 3WKW | Crystal structure of GH127 beta-L-arabinofuranosidase HYPBA1 from bifidobacterium longum ligand… | x-ray diffraction | A | — | — |
| 3WKX | Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose… | x-ray diffraction | A | — | — |
| 3WKX | Crystal structure of GH127 beta-L-arabinofuranosidase HYPBA1 from bifidobacterium longum arabinose… | x-ray diffraction | A | — | — |
| 3WRE | The crystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 | x-ray diffraction | A | — | — |
| 3WRE | The crystal structure of native HYPBA1 from bifidobacterium longum jcm 1217 | x-ray diffraction | A | — | — |
| 3WRF | The crystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 | x-ray diffraction | A | — | — |
| 3WRF | The crystal structure of native HYPBA1 from bifidobacterium longum jcm 1217 | x-ray diffraction | A | — | — |
| 3WRG | The complex structure of HypBA1 with L-arabinose | x-ray diffraction | A | — | — |
| 3WRG | The complex structure of HYPBA1 with L-arabinose | x-ray diffraction | A | — | — |
| 7BZL | GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with beta-L-arabinofuranose-configured… | x-ray diffraction | A | ZN, FE0 | 4 (best 0.68) |
| 7BZL | GH127 beta-L-arabinofuranosidase HYPBA1 covalently complexed with beta-L-arabinofuranose-configured… | x-ray diffraction | A | ZN, FE0 | — |
| 7DIF | GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with beta-L-arabinofuranose-configured… | x-ray diffraction | A | ZN, FE0, K | 3 (best 0.70) |
| 7DIF | GH127 beta-L-arabinofuranosidase HYPBA1 covalently complexed with beta-L-arabinofuranose-configured… | x-ray diffraction | A | ZN, FE0, K | — |
| 7EXU | GH127 beta-L-arabinofuranosidase HypBA1 E322Q mutant complexed with p-nitrophenyl… | x-ray diffraction | A | ZN, 07Y | 3 (best 0.65) |
| 7EXU | GH127 beta-L-arabinofuranosidase HYPBA1 E322Q mutant complexed with P- nitrophenyl… | x-ray diffraction | A | ZN, 07Y | — |
| 7EXV | GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with beta-L-arabinofuranoylamide | x-ray diffraction | A | ZN, 08U | 3 (best 0.67) |
| 7EXV | GH127 beta-L-arabinofuranosidase HYPBA1 covalently complexed with beta-L-arabinofuranoylamide | x-ray diffraction | A | ZN, 08U | — |
| 7EXW | GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with alpha-L-arabinofuranosylamide | x-ray diffraction | A | 09X, ZN | 3 (best 0.67) |
| 7EXW | GH127 beta-L-arabinofuranosidase HYPBA1 covalently complexed with alpha-L-arabinofuranosylamide | x-ray diffraction | A | 09X, ZN | — |
| 8QF2 | Beta-L-Arabinofurano-cyclitol Aziridines are Cysteine-directed Broad-spectrum Inhibitors and… | x-ray diffraction | A | ZN, UI5 | 3 (best 0.70) |
| E8MGH8 | AlphaFold monomer V2.0 prediction for non-reducing end beta-L- arabinofuranosidase (E8MGH8) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 11 records
- FE0 · (1S,2S,3R,4R)-3-(hydroxymethyl)cyclopentane-1,2,4-triol · in 4 records
- 07Y · (2S,3R,4R,5R)-2-(hydroxymethyl)-5-(4-nitrophenoxy) oxolane-3,4-diol · in 2 records
- 08U · 2-bromanyl-N-[(2S,3R,4R,5S)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]ethanamide · in 2 records
- 09X · 2-bromanyl-N-[(2R,3R,4R,5S}-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]ethanamide · in 2 records
- K · Potassium ion · in 2 records
- UI5 · (1~{S},2~{S},3~{S},4~{R})-4-azanyl-3-(hydroxymethyl)cyclopentane-1,2-diol · in 1 record
Experiment against prediction
- 7EXV chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.66 Å
- 7EXV chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.66 Å
- 7EXU chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.65 Å
- 7EXU chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.65 Å
- 7DIF chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.75 Å
- 7DIF chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.75 Å
- 3WKX chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.76 Å
- 3WKX chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.76 Å
- 7BZL chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.76 Å
- 7BZL chain A against the predicted model E8MGH8: TM-score 0.99, RMSD 0.76 Å
Elsewhere
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