Crystal structure of CCM3 in complex with the C-terminal regulatory domain of STK25

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1725 Ų buried · 16 hydrogen bonds · protein-protein

Compared structures

• 3W8H · Crystal structure of CCM3 in complex with the C-terminal regulatory domain of STK25 · the same entry in another collection · chain A against A, TM-score 1.00
• Q9BUL8 · AlphaFold monomer V2.0 prediction for programmed cell death protein 10 (Q9BUL8) · a predicted model of the same protein · chain A against A, TM-score 0.95
• O00506 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 25 (O00506) · a predicted model of the same protein · chain B against A, TM-score 0.86

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9BUL8
• Every structure of UniProt O00506
• Elsewhere: RCSB PDB 3W8H · PDBe 3W8H · UniProt Q9BUL8 · UniProt O00506