Crystal structure of amidohydrolase NIS_0429 (target efi-500396) from nitratiruptor sp. SB155-2

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 25% strand (DSSP).

Ligands and binding sites

• BCT · Bicarbonate ion · ligand · 2 copies · chains A
• UNL · Unknown ligand · ligand · 2 copies · chains A
• BEZ · Benzoic acid · ligand · chains A
• FE · Fe (III) ion · metal · chains A
• K · Potassium ion · metal · chains A
• TLA · L(+)-tartaric acid · additive · 2 copies · chains A
• GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

• 3V7P · Crystal structure of amidohydrolase nis_0429 (target efi-500396) from Nitratiruptor sp.… · the same entry in another collection · chain A against A, TM-score 1.00
• A6Q234 · AlphaFold monomer V2.0 prediction for aminodeoxyfutalosine deaminase (A6Q234) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A6Q234
• Elsewhere: RCSB PDB 3V7P · PDBe 3V7P · UniProt A6Q234