MolNFT v1 · #81890 · protein
Structure of FBXL5 hemerythrin domain, C2 cell, grown anaerobically
3V5Z · F-BOX/LRR-repeat protein 5: “Structure of FBXL5 hemerythrin domain, C2 cell, grown anaerobically”. X-ray diffraction, 1 ligand (FEO), 1 pocket (best druggability 0.82). MolNFT v1 #81890 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3V5Z
- Type
- protein
- Length
- 309 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- F-BOX/LRR-repeat protein 5
- UniProt
- Q9UKA1
- Ligands
- FEO
- Pockets
- 1 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 83% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | F-BOX/LRR-repeat protein 5 | protein | 154 | 84% helix, 0% strand | Q9UKA1 |
| B | F-BOX/LRR-repeat protein 5 | protein | 155 | 83% helix, 0% strand | Q9UKA1 |
Ligands and binding sites
- FEO · Mu-oxo-diiron · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1020 | 0.82 | 0.83 | 77 | empty |
Interfaces
1 interface between chains.
- A–B · 931 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 3V5Z · Structure of FBXL5 hemerythrin domain, C2 cell, grown anaerobically · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UKA1 · AlphaFold monomer V2.0 prediction for F-BOX/LRR-repeat protein 5 (Q9UKA1) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UKA1
- Elsewhere: RCSB PDB 3V5Z · PDBe 3V5Z · UniProt Q9UKA1
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