MolNFT v1 · #81825 · protein

Crystal structure of the N-terminal fragment of zebrafish TLR5

3V44 · Toll-like receptor 5B and variable lymphocyte receptor B.61…: “Crystal structure of the N-terminal fragment of zebrafish TLR5”. X-ray diffraction, 1 ligand (NAG), 1 pocket (best druggability 0.29). MolNFT v1 #81825 on GenesisL1: 3D…

PDB: 3V44
Type: protein
Length: 401 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Toll-like receptor 5B and variable lymphocyte receptor B.61 chimeric protein
UniProt: B3DIN1, Q4G1L2
Ligands: NAG
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Toll-like receptor 5B and variable lymphocyte receptor B.61 chimeric protein	protein	401	11% helix, 17% strand	B3DIN1, Q4G1L2

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.29	0.75	15	empty

Modifications

Observed in the structure: 4 disulfide, 3 glycan (disulfide, N-glycosylation).

Compared structures

3V44 · Crystal structure of the N-terminal fragment of zebrafish TLR5 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B3DIN1
Every structure of UniProt Q4G1L2
Elsewhere: RCSB PDB 3V44 · PDBe 3V44 · UniProt B3DIN1 · UniProt Q4G1L2

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