MolNFT v1 · #81696 · protein

The structure of the ribosomal RNA small subunit methyltransferase a from burkholderia pseudomallei

3UZU: “The structure of the ribosomal RNA small subunit methyltransferase a from burkholderia pseudomallei”. X-ray diffraction, 1 pocket (best druggability 0.67). MolNFT v1 #81696 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3UZU
Type: protein
Length: 262 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribosomal RNA small subunit methyltransferase a
EC: 2.1.1.182
UniProt: Q3JVW6
Pockets: 1 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribosomal RNA small subunit methyltransferase a (EC 2.1.1.182)	protein	262	45% helix, 21% strand	Q3JVW6

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	361	0.67	0.81	41	empty

Compared structures

3UZU · The structure of the Ribosomal RNA small subunit methyltransferase A from Burkholderia… · the same entry in another collection · chain A against A, TM-score 1.00
Q3JVW6 · AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase a… · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3JVW6
Elsewhere: RCSB PDB 3UZU · PDBe 3UZU · UniProt Q3JVW6

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