MolNFT v1 · #81659 · protein
BLAR1 sensor domain from staphylococcus aureus with N439V mutation
3UY6 · Regulatory protein BLAR1: “BLAR1 sensor domain from staphylococcus aureus with N439V mutation”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.77). MolNFT v1 #81659 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3UY6
- Type
- protein
- Length
- 504 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory protein BLAR1
- UniProt
- P18357
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Regulatory protein BLAR1 | protein | 252 | 35% helix, 26% strand | P18357 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1028 | 0.77 | 0.79 | 96 | GOL |
| 2 | 89 | 0.35 | 0.75 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 573 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 3UY6 · BlaR1 sensor domain from Staphylococcus aureus with N439V mutation · the same entry in another collection · chain A against A, TM-score 1.00
- P18357 · AlphaFold monomer V2.0 prediction for regulatory protein BLAR1 (P18357) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18357
- Elsewhere: RCSB PDB 3UY6 · PDBe 3UY6 · UniProt P18357
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