MolNFT v1 · #81624 · protein
Crystal structure of a RNA binding domain of poly-U binding splicing factor 60KDA (PUF60) from homo sapiens at 2.50 a resolution
3UWT · POLY(U)-binding-splicing factor PUF60: “Crystal structure of a RNA binding domain of poly-U binding splicing factor 60KDA (PUF60) from homo sapiens…”. X-ray diffraction, 1 ligand (CL), 1 pocket (best druggability 0.34). MolNFT v1…
- PDB
- 3UWT
- Type
- protein
- Length
- 197 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- POLY(U)-binding-splicing factor PUF60
- UniProt
- Q9UHX1
- Ligands
- CL
- Pockets
- 1 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POLY(U)-binding-splicing factor PUF60 | protein | 197 | 32% helix, 26% strand | Q9UHX1 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.34 | 0.73 | 21 | empty |
Modifications
Observed in the structure: 7 modified (engineered).
Compared structures
- 3UWT · Crystal structure of a RNA binding domain of poly-U binding splicing factor 60KDa (PUF60)… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UHX1 · AlphaFold monomer V2.0 prediction for POLY(U)-binding-splicing factor PUF60 (Q9UHX1) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UHX1
- Elsewhere: RCSB PDB 3UWT · PDBe 3UWT · UniProt Q9UHX1
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