MolNFT v1 · #81571 · protein

Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit bptf

3UV2: “Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit bptf”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #81571 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3UV2
Type: protein
Length: 119 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bromodomain of human nucleosome-remodeling factor subunit bptf
UniProt: Q12830
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Bromodomain of human nucleosome-remodeling factor subunit bptf	protein	119	70% helix, 2% strand	Q12830

Ligands and binding sites

7PE · 2-(2-(2-(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)ethoxy) ethoxy)ethanol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.50	0.83	18	7PE

Compared structures

3UV2 · Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit BPTF · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q12830
Elsewhere: RCSB PDB 3UV2 · PDBe 3UV2 · UniProt Q12830

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