MolNFT v1 · #81469 · protein
Crystal structure of the periplasmic sugar binding protein chve
3URM · Multiple sugar-binding periplasmic receptor chve: “Crystal structure of the periplasmic sugar binding protein chve”. X-ray diffraction, 1 ligand (GAL), 3 pockets (best druggability 0.73). MolNFT v1 #81469 on GenesisL1: 3D structure…
- PDB
- 3URM
- Type
- protein
- Length
- 658 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Multiple sugar-binding periplasmic receptor chve
- UniProt
- P25548
- Ligands
- GAL
- Pockets
- 3 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Multiple sugar-binding periplasmic receptor chve | protein | 329 | 46% helix, 16% strand | P25548 |
Ligands and binding sites
- GAL · beta-D-galactopyranose · sugar · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 686 | 0.73 | 0.79 | 64 | empty |
| 2 | 767 | 0.70 | 0.76 | 72 | empty |
| 3 | 68 | 0.68 | 0.95 | 25 | GAL |
Interfaces
1 interface between chains.
- A–B · 894 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 3URM · Crystal structure of the periplasmic sugar binding protein ChvE · the same entry in another collection · chain A against A, TM-score 1.00
- P25548 · AlphaFold monomer V2.0 prediction for multiple sugar-binding periplasmic receptor chve… · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25548
- Elsewhere: RCSB PDB 3URM · PDBe 3URM · UniProt P25548
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