MolNFT v1 · #80636 · protein

Crystal structure of human glycogenin-1 (GYG1) complexed with manganese

3U2T: “Crystal structure of human glycogenin-1 (GYG1) complexed with manganese”. X-ray diffraction, 1 ligand (MN), 2 pockets (best druggability 0.49). MolNFT v1 #80636 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3U2T
Type: protein
Length: 256 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycogenin-1
EC: 2.4.1.186
UniProt: P46976
Ligands: MN
Pockets: 2 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycogenin-1 (EC 2.4.1.186)	protein	256	42% helix, 20% strand	P46976

Ligands and binding sites

MN · Manganese (II) ion · metal · chains A
EDO · 1,2-ethanediol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.49	0.82	20	empty
2	177	0.47	0.76	24	empty

Compared structures

3U2T · Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese · the same entry in another collection · chain A against A, TM-score 1.00
P46976 · AlphaFold monomer V2.0 prediction for glycogenin-1 (P46976) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P46976
Elsewhere: RCSB PDB 3U2T · PDBe 3U2T · UniProt P46976

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