MolNFT v1 · #80233 · protein
Structure of the transcriptional regulator of the gntr family, from coxiella burnetii.
3TQN · Transcriptional regulator, gntr family: “Structure of the transcriptional regulator of the gntr family, from coxiella burnetii.”. X-ray diffraction, 5 pockets (best druggability 0.47). MolNFT v1 #80233 on GenesisL1: 3D structure…
- PDB
- 3TQN
- Type
- protein
- Length
- 314 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, gntr family
- UniProt
- Q83DG1
- Pockets
- 5 · best druggability 0.47
Structure
x-ray diffraction · 3 distinct chains · 47% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, gntr family | protein | 107 | 49% helix, 9% strand | Q83DG1 |
| B | Transcriptional regulator, gntr family | protein | 108 | 51% helix, 8% strand | Q83DG1 |
| C | Transcriptional regulator, gntr family | protein | 99 | 41% helix, 6% strand | Q83DG1 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.47 | 0.74 | 31 | empty |
| 2 | 141 | 0.46 | 0.77 | 25 | empty |
| 3 | 56 | 0.38 | 0.79 | 12 | empty |
| 4 | 71 | 0.38 | 0.77 | 16 | empty |
| 5 | 80 | 0.33 | 0.74 | 16 | empty |
Interfaces
2 interfaces between chains.
- A–C · 632 Ų buried · 1 hydrogen bond · protein-protein
- A–B · 614 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 3TQN · Structure of the transcriptional regulator of the GntR family, from Coxiella burnetii. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83DG1
- Elsewhere: RCSB PDB 3TQN · PDBe 3TQN · UniProt Q83DG1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.