Research workbench
Structure of the transcriptional regulator of the gntr family, from coxiella burnetii.
Analyse Structure of the transcriptional regulator of the gntr family, from coxiella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3TQN
- Type
- protein
- Length
- 314 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, gntr family
- UniProt
- Q83DG1
- Pockets
- 5 · best druggability 0.47
Structure
x-ray diffraction · 3 distinct chains · 47% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, gntr family | protein | 107 | 49% helix, 9% strand | Q83DG1 |
| B | Transcriptional regulator, gntr family | protein | 108 | 51% helix, 8% strand | Q83DG1 |
| C | Transcriptional regulator, gntr family | protein | 99 | 41% helix, 6% strand | Q83DG1 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.47 | 0.74 | 31 | empty |
| 2 | 141 | 0.46 | 0.77 | 25 | empty |
| 3 | 56 | 0.38 | 0.79 | 12 | empty |
| 4 | 71 | 0.38 | 0.77 | 16 | empty |
| 5 | 80 | 0.33 | 0.74 | 16 | empty |
Interfaces
2 interfaces between chains.
- A–C · 632 Ų buried · 1 hydrogen bond · protein-protein
- A–B · 614 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 3TQN · Structure of the transcriptional regulator of the GntR family, from Coxiella burnetii. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83DG1
- Elsewhere: RCSB PDB 3TQN · PDBe 3TQN · UniProt Q83DG1
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