MolNFT v1 · #80051 · protein
Microcin C7 self immunity protein mccf in the wild type apo state
3TLA: “Microcin C7 self immunity protein mccf in the wild type apo state”. X-ray diffraction, 6 pockets (best druggability 0.60). MolNFT v1 #80051 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3TLA
- Type
- protein
- Length
- 670 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mccf
- UniProt
- Q2KKH9
- Pockets
- 6 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Mccf | protein | 335 | 31% helix, 23% strand | Q2KKH9 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.60 | 0.88 | 20 | EDO |
| 2 | 292 | 0.57 | 0.77 | 43 | empty |
| 3 | 270 | 0.56 | 0.77 | 36 | empty |
| 4 | 93 | 0.55 | 0.85 | 25 | empty |
| 5 | 55 | 0.31 | 0.75 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 1886 Ų buried · 43 hydrogen bonds · protein-protein
Compared structures
- 3TLA · Microcin C7 self immunity protein MccF in the wild type APO state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2KKH9
- Elsewhere: RCSB PDB 3TLA · PDBe 3TLA · UniProt Q2KKH9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.