MolNFT v1 · #79060 · protein
Crystal structure of holo D-serine dehydratase from escherichia COLI at 1.97 a resolution
3SS9: “Crystal structure of holo D-serine dehydratase from escherichia COLI at 1.97 a resolution”. X-ray diffraction, 2 ligands (PLP, K), 2 pockets (best druggability 0.75). MolNFT v1 #79060 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3SS9
- Type
- protein
- Length
- 431 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- D-serine dehydratase
- EC
- 4.3.1.18
- UniProt
- P00926
- Ligands
- PLP, K
- Pockets
- 2 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | D-serine dehydratase (EC 4.3.1.18) | protein | 431 | 54% helix, 15% strand | P00926 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.75 | 0.97 | 32 | PLP |
| 2 | 62 | 0.31 | 0.76 | 19 | empty |
Modifications
Observed in the structure: 1 cofactor (pyridoxal phosphate Schiff base).
Compared structures
- 3SS9 · Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.97 A resolution · the same entry in another collection · chain X against X, TM-score 1.00
- P00926 · AlphaFold monomer V2.0 prediction for D-serine dehydratase (P00926) · a predicted model of the same protein · chain X against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00926
- Elsewhere: RCSB PDB 3SS9 · PDBe 3SS9 · UniProt P00926
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