MolNFT v1 · #78910 · protein

Crystal structure of nucleotide-free human DYNAMIN1

3SNH · Dynamin-1: “Crystal structure of nucleotide-free human DYNAMIN1”. X-ray diffraction, 9 pockets (best druggability 0.69). MolNFT v1 #78910 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3SNH
Type: protein
Length: 652 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dynamin-1
EC: 3.6.5.5
UniProt: Q05193
Pockets: 9 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dynamin-1 (EC 3.6.5.5)	protein	652	50% helix, 12% strand	Q05193

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	607	0.69	0.78	45	empty
2	349	0.59	0.77	40	empty
3	64	0.52	0.86	25	empty
4	120	0.46	0.78	25	empty
5	105	0.44	0.78	19	empty

Compared structures

3SNH · Crystal structure of nucleotide-free human dynamin1 · the same entry in another collection · chain A against A, TM-score 1.00
Q05193 · AlphaFold monomer V2.0 prediction for dynamin-1 (Q05193) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05193
Elsewhere: RCSB PDB 3SNH · PDBe 3SNH · UniProt Q05193

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.