MolNFT v1 · #78861 · RNA
Crystal structure of the 2'- deoxyguanosine riboswitch bound to guanosine-5'-monophosphate
3SLQ · RNA (68-mer): “Crystal structure of the 2'- deoxyguanosine riboswitch bound to guanosine-5'-monophosphate”. X-ray diffraction, 2 ligands (5GP, SO4), 3 pockets (best druggability 0.74). MolNFT v1 #78861 on GenesisL1: 3D structure…
- PDB
- 3SLQ
- Type
- RNA
- Length
- 136 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA (68-mer)
- Ligands
- 5GP, SO4
- Pockets
- 3 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | RNA (68-mer) | rna | 68 | — | — |
Ligands and binding sites
- 5GP · Guanosine-5'-monophosphate · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 7 copies · chains A, B
- SIN · Succinic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1072 | 0.74 | 0.78 | 58 | 5GP, SO4 |
| 2 | 1095 | 0.70 | 0.76 | 56 | SO4 |
| 3 | 176 | 0.47 | 0.77 | 17 | 5GP |
Interfaces
1 interface between chains.
- A–B · 393 Ų buried · 29 hydrogen bonds · nucleic-nucleic
Modifications
Observed in the structure: 4 modified (nucleotide modification).
Compared structures
- 3SLQ · Crystal structure of the 2'- Deoxyguanosine riboswitch bound to guanosine-5'-monophosphate · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3SLQ · PDBe 3SLQ
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.