MolNFT v1 · #77780 · protein

Crystal structure of klebsiella pneumoniae hpxo complexed with FAD

3RP6 · Flavoprotein monooxygenase: “Crystal structure of klebsiella pneumoniae hpxo complexed with FAD”. X-ray diffraction, 1 ligand (FAD), 1 pocket (best druggability 0.79). MolNFT v1 #77780 on GenesisL1: 3D structure, binding sites and…

PDB: 3RP6
Type: protein
Length: 392 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flavoprotein monooxygenase
UniProt: A6T923
Ligands: FAD
Pockets: 1 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flavoprotein monooxygenase	protein	392	37% helix, 26% strand	A6T923

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	956	0.79	0.81	89	FAD

Modifications

Observed in the structure: 11 modified (engineered).

Compared structures

3RP6 · Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD · the same entry in another collection · chain A against A, TM-score 1.00
A6T923 · AlphaFold monomer V2.0 prediction for FAD-dependent urate hydroxylase (A6T923) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A6T923
Elsewhere: RCSB PDB 3RP6 · PDBe 3RP6 · UniProt A6T923

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