X-ray structure of the C-terminal swapped dimer of P114A variant of ribonuclease a

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 39% strand (DSSP).

Ligands and binding sites

• CGP · 2'-deoxycytidine-2'-deoxyguanosine-3',5'-monophosphate · ligand · 4 copies · chains A, B, C, D
• PO4 · Phosphate ion · ion · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Interfaces

3 interfaces between chains.

• C–D · 1889 Ų buried · 38 hydrogen bonds · protein-protein
• A–B · 1859 Ų buried · 37 hydrogen bonds · protein-protein
• B–D · 99 Ų buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 16 disulfide (disulfide).

Compared structures

• 3RID · X-ray structure of the C-terminal swapped dimer of P114A variant of Ribonuclease A · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P61823
• Elsewhere: RCSB PDB 3RID · PDBe 3RID · UniProt P61823