MolNFT v1 · #76846 · protein + DNA

Human topoisomerase iibeta in complex with DNA and etoposide

3QX3: “Human topoisomerase iibeta in complex with DNA and etoposide”. X-ray diffraction. MolNFT v1 #76846 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3QX3
Type: protein + DNA
Length: 1,382 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q02880

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	671	—	Q02880
B	—	protein	671	—	Q02880
C, E	—	dna	8	—	—
D, F	—	dna	12	—	—

Compared structures

3QX3 · Human topoisomerase IIbeta in complex with DNA and etoposide · the same entry in another collection · chain F against F, TM-score 1.00
Q02880 · AlphaFold monomer V2.0 prediction for DNA topoisomerase 2-beta (Q02880) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q02880
Elsewhere: RCSB PDB 3QX3 · PDBe 3QX3 · UniProt Q02880

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