MolNFT v1 · #76222 · protein
Sheep liver sorbitol dehydrogenase
3QE3: “Sheep liver sorbitol dehydrogenase”. X-ray diffraction, 1 ligand (ZN), 3 pockets (best druggability 0.71). MolNFT v1 #76222 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3QE3
- Type
- protein
- Length
- 351 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sorbitol dehydrogenase
- EC
- 1.1.1.14
- UniProt
- P07846
- Ligands
- ZN
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorbitol dehydrogenase (EC 1.1.1.14) | protein | 351 | 32% helix, 27% strand | P07846 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
- ACY · Acetic acid · additive · 3 copies · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 626 | 0.71 | 0.79 | 58 | ZN, GOL, ACY |
| 2 | 118 | 0.43 | 0.76 | 21 | ACY |
| 3 | 85 | 0.41 | 0.78 | 17 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07846
- Elsewhere: RCSB PDB 3QE3 · PDBe 3QE3 · UniProt P07846
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