MolNFT v1 · #76125 · protein
Paramecium chlorella bursaria VIRUS1 putative orf A654L is a polyamine acetyltransferase
3QB8 · A654L protein: “Paramecium chlorella bursaria VIRUS1 putative orf A654L is a polyamine acetyltransferase”. X-ray diffraction, 1 ligand (COA), 3 pockets (best druggability 0.70). MolNFT v1 #76125 on GenesisL1: 3D structure, binding…
- PDB
- 3QB8
- Type
- protein
- Length
- 394 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- A654L protein
- UniProt
- O41136
- Ligands
- COA
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | A654L protein | protein | 197 | 43% helix, 25% strand | O41136 |
Ligands and binding sites
- COA · Coenzyme A · ligand · 2 copies · chains A, B
- IMD · Imidazole · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 253 | 0.70 | 0.85 | 43 | COA, IMD |
| 2 | 238 | 0.68 | 0.84 | 45 | COA, IMD |
| 3 | 102 | 0.42 | 0.78 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 511 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 3QB8 · Paramecium Chlorella Bursaria Virus1 Putative ORF A654L is a Polyamine Acetyltransferase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O41136
- Elsewhere: RCSB PDB 3QB8 · PDBe 3QB8 · UniProt O41136
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