MolNFT v1 · #75670 · protein

Rta in complex with 7-carboxy-pterin

3PX8 · Preproricin: “Rta in complex with 7-carboxy-pterin”. X-ray diffraction, 1 ligand (JP2), 3 pockets (best druggability 0.56). MolNFT v1 #75670 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3PX8
Type: protein
Length: 258 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Preproricin
UniProt: D6MWP9
Ligands: JP2
Pockets: 3 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Preproricin	protein	258	41% helix, 22% strand	D6MWP9

Ligands and binding sites

JP2 · 2-amino-4-oxo-1,4-dihydropteridine-7-carboxylic acid · ligand · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	150	0.56	0.82	26	empty
2	73	0.45	0.82	16	JP2
3	50	0.33	0.77	12	empty

Compared structures

3PX8 · RTA in complex with 7-carboxy-pterin · the same entry in another collection · chain X against X, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D6MWP9
Elsewhere: RCSB PDB 3PX8 · PDBe 3PX8 · UniProt D6MWP9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.